Evidence-Based Medicine Pyramid

Link to EBM images.

I am thrilled that my page has gotten a few people turned on to evidence based medicine. I refuse, though, to try to teach statistical analysis, though, as I don’t think I’m very good at it. I am sharing this pyramid which is easy to understand and helps one see why I feel that some studies are better than others and why some studies get published in not-so-good journals and others get published in NEJM and The Lancet. As noted at the bottom of the image, my opinion from practical observation is 💩which is why you should always read data for yourself and not trust what I write and say. I hope I don’t upset the copyright gods bc stealing someone’s image.

-EJ

Although great care has been taken to ensure that the information in this post is accurate, eddyjoemd, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

The effect of melatonin on delirium in hospitalised patients: A systematic review and meta-analyses with trial sequential analysis

Link to Abstract

Link to PDF

We are all trying to combat delirium by all possible means. Getting pts their glasses and hearing aides. Keeping the lights on during the day. Having family around to speak to them. We’ve also had recent trials which have been quite disappointing using medications. Could there be a good cheap medication to prevent #delirium? This paper on using #melatonin is a strong meta analysis that looks into this and could potentially change my practice... but not for the reasons on the surface. I’ve even recently heard of using melatonin for sepsis, but that’s a discussion for another day and something else I’m going to dig into. Either way, a 🎩 tip to the authors.

-EJ

Although great care has been taken to ensure that the information in this post is accurate, eddyjoemd, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

Hyperkalemia in patients with kidney disease: how to manage it

Link to Abstract

Full Free PDF

#hyperkalemia, a daily issue for the #intensivist, #emergencymedicine docs, and #nephrologist. It’s really not that hard to manage once you check your own pulse. This tasty little algorithm definitely puts the adrenaline in check after you see that number called in as a critical from the lab and shows up glowing red on your computer screen telling you to just do something! A 🎩 tip to the authors.

-EJ

Although great care has been taken to ensure that the information in this post is accurate, eddyjoemd, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

Adjunctive Intermittent Pneumatic Compression for Venous Thromboprophylaxis

Link to Abstract. Not a free article. :(

This is a question I would always ask myself as I would check off the boxes on admission orders as a resident, not as a fellow because the residents do it, and sometimes now as an attending. I always thought it was a waste of resources and uncomfortable to the patients to not only inject them with pharmacological DVTs prophylaxis, but also burden them with those SCDs. I’m really grateful for my colleagues in Saudi Arabia for putting together this study and sealing the deal for me as to how to manage this moving forward. A definite 🎩 tip to them

-EJ

Although great care has been taken to ensure that the information in this post is accurate, eddyjoemd, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

Mortality rate and other clinical features observed in Open vs closed format intensive care units

Link to article website

Direct link to PDF

Although great care has been taken to ensure that the information in this post is accurate, eddyjoemd, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome

Link to Abstract

Link to PDF

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Noninvasive Ventilation in Acute Hypoxemic Respiratory Failure

Link to Abstract

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High flow nasal cannulae oxygen therapy in acute-moderate hypercapnic respiratory failure

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Although great care has been taken to ensure that the information in this post is accurate, eddyjoemd, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome

Link to Abstract

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ARDS: Formal Guidelines

Link to Abstract

Link to PDF

Although great care has been taken to ensure that the information in this post is accurate, eddyjoemd, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.