Sunday, August 4, 2019

Balanced Crystalloids Versus Saline in Critically Ill Adults: A Systematic Review and Meta-analysis



Link to Abstract

I honestly wonder how much data is enough data to change some minds. This is why I am counting on you all, people who are trying to keep up with this flurry of data to the best of your ability, to go through medical school, residency, possibly fellowship with a healthy respect for 0.9% saline solution. It may seem like it's hopeless from time to time to change decades worth of practice. Heck, my first IVF resuscitation video is almost 2.5 years old and has almost 39000 views! Hopefully the studies which will be published within the upcoming 2 years will hit the nail on the head. You can see the data from the slides, using saline versus balanced salt solutions increased mortality in the critically ill, increased acute kidney injury, and kept the patients on the ventilator for a longer period of time. To those harping about the increased costs of one fluid versus the next, consider the cost of one ventilator day. Consider the risks involved with each day on the vent. Consider the financial strain from working up every-single-case of AKI. This stuff adds up, colleagues. Anyway. A hat tip to the authors! 


- EJ







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